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A Senior Design Project in Fabrication of Microfluidic HIV/Zika Viral Load and Monitoring Test Chips through Manufacturing Processes

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2018 ASEE Annual Conference & Exposition


Salt Lake City, Utah

Publication Date

June 23, 2018

Start Date

June 23, 2018

End Date

July 27, 2018

Conference Session

Capstone Projects in Manufacturing

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Richard Chiou Drexel University (Eng. & Eng. Tech.)

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Dr. Richard Chiou is Associate Professor within the Engineering Technology Department at Drexel University, Philadelphia, USA. He received his Ph.D. degree in the G.W. Woodruff School of Mechanical Engineering at Georgia Institute of Technology. His educational background is in manufacturing with an emphasis on mechatronics. In addition to his many years of industrial experience, he has taught many different engineering and technology courses at undergraduate and graduate levels. His tremendous research experience in manufacturing includes environmentally conscious manufacturing, Internet based robotics, and Web based quality. In the past years, he has been involved in sustainable manufacturing for maximizing energy and material recovery while minimizing environmental impact.

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Michael G Mauk P.E. Drexel University

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Michael Mauk is Assistant Professor in Drexel University's Engineering Technology program.

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Carlos Michael Ruiz Drexel University (Eng. & Eng. Tech.)

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Current Techniques of diagnostics use expensive laboratory equipment. These costs are levied upon the patient. Medical costs have increased to astronomical numbers and have crippled the accessibility to healthcare technology. Simplified miniaturized laboratory processes are considered ‘lab on a chip’ medical diagnostics devices. In recent years, microfluidic projects have proved highly effective in introducing traditional engineering students (electrical, mechanical, and industrial) to clinical diagnostics and the emerging field of point-of-care (POC) tests. POC tests will enable new paradigms in the delivery of sustainable healthcare for resource-limited areas of the world, and foster more personalized and customized medical care in developed countries. This senior design project consisted of students within biomedical, electrical, and mechanical engineering. As these projects can be ambitious and students may not have familiarity with certain aspects of this technology, good management is needed to streamline activities and keep the effort focused and on schedule.

The project is leveraged towards engineering student skills in CAD, prototyping, image processing, instrumentation, and control. Students had to utilize manufacturing methods and techniques to create such medical devices. This was a capstone project that was evaluated for three consecutive terms. The students had no prior experience within diagnostics but learned a great deal of information from extensive instigation and collaborative consultants from XXX University. The students experienced mechanical and biomedical application to produce a medical device with accessibility to a mechanical and virology laboratory. They were in direct contact with industry manufactures to determine marketability. Our Senior Design projects are evaluated by a panel of about 30 Faculty from our own school, as well as faculty from neighboring institutions, engineers from industry and research organizations, and independent consulting engineers. This project received first place within the university’s engineering competition.

Chiou, R., & Mauk, M. G., & Ruiz, C. M. (2018, June), A Senior Design Project in Fabrication of Microfluidic HIV/Zika Viral Load and Monitoring Test Chips through Manufacturing Processes Paper presented at 2018 ASEE Annual Conference & Exposition , Salt Lake City, Utah. 10.18260/1-2--29722

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