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Session 1309

A Simulation-Based Teaching and Learning Resource for Electrophysiology: iCell

Semahat S. Demir

Joint Biomedical Engineering Program, University of Memphis & University of Tennessee 330 Engineering Technology Building, Memphis TN, 38152-3210, USA Email: sdemir@memphis.edu

Abstract— An interactive web resource, iCell (http://ssd1.bme.memphis.edu/icell/), was developed as a simulation-based teaching and learning tool for electrophysiology. The web site integrates education and research, and provides JAVA applets that represent models of various cardiac cells and neurons, and simulation data of their bioelectric activities at cellular level. Each JAVA-based model allows the user to go through menu options to change model parameters, run and view simulation results. The site also hosts a glossary section for the scientific terms. iCell has been used as a teaching and learning tool for five graduate courses at the Joint Biomedical Engineering Program of University of Memphis and University of Tennessee. This modeling tool has been also used as a collaboration site among our colleagues interested in simulations of cell membrane activities. Scientists from the fields of biosciences, engineering, life sciences and medical sciences in Argentina, Belgium, Brazil, Canada, China, England, Germany, Greece, Ireland, the Netherlands, New Zealand, Republic of Korea, Spain, Turkey and USA have tested and utilized iCell as a simulation-based teaching, learning and collaboration environment. The cellular modeling resource, iCell, provides us with a platform- independent, interactive and user-friendly teaching and learning tool, and also a collaboration environment for electrophysiology to be shared over the Internet.

Keywords: computational tool for electrophysiology; single cell models; simulation data, computational JAVA models; internet application.

Introduction

The interactive cell modeling internet resource, iCell, integrates research and education for electrophysiology. The site is located at http://ssd1.bme.memphis.edu/icell/. iCell consists of JAVA applets representing models of various cardiac cells and neurons, and provides simulation data of their bioelectric activities at single cell level. Each JAVA-based cell model gives an overview of the cell, demonstrates the cell membrane with an electrical equivalent circuit and cites the published modeling paper for further information (as seen in Figure1). The cell models in iCell are grouped into versions, and cardiac or neuron "modelboxes".

Proceedings of the 2003 American Society for Engineering Education Annual Conference & Exposition Copyright © 2003, American Society for Engineering Education

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Demir, S. S. (2003, June), A Simulation Based Teaching And Learning Resource For Electrophysiology: Icell Paper presented at 2003 Annual Conference, Nashville, Tennessee. 10.18260/1-2--11857