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Development and Assessment of a Textbook for Tissue Engineering Lab Instruction

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2012 ASEE Annual Conference & Exposition


San Antonio, Texas

Publication Date

June 10, 2012

Start Date

June 10, 2012

End Date

June 13, 2012



Conference Session

BME Laboratory and Project Experiences

Tagged Division


Page Count


Page Numbers

25.440.1 - 25.440.8



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Paper Authors


Melissa Kurtis Micou University of California, San Diego

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Melissa Kurtis Micou is a lecturer in the Department of Bioengineering at the University of California, San Diego. She has taught tissue engineering lecture and lab courses to undergraduate students for the past seven years.

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Dawn M. Kilkenny Ph.D. University of Toronto

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Dawn Kilkenny earned her Ph.D. in physiology from the University of Western Ontario, Canada, and trained as a postdoctoral fellow in Immunology at Vanderbilt University, Nashville, Tenn. She subsequently worked for four years as a Senior Research Specialist at the Vanderbilt Cell Imaging Resource (CISR) microscope facility, and is currently an Assistant Professor at the Institute of Biomaterials and Biomedical Engineering (IBBME), University of Toronto. She is also the Academic Advisor to the IBBME Undergraduate Teaching Laboratory.

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Development and Assessment of a Textbook for Tissue Engineering Lab Instruction During the past ten years there has been a tremendous increase in the number ofbiomedical engineering / bioengineering (BME/BE) programs offering lecture courses intissue engineering (TE). Currently, nearly seventy percent of ABET accredited BME/BEprograms offer a TE lecture course, yet only roughly fifteen percent offer a labcomponent or separate lab course. Given that engineering is an applied field, the benefitsof hands-on lab experience are clear. Therefore, the small number of existing TE labcourses may be attributed to the relatively recent emergence of the field and the lack ofavailable instructional materials. A new textbook, written by the authors and entitled A Laboratory Course inTissue Engineering, will be published by Taylor Francis and CRC Press next year. Thelab manual is appropriate for upper-division undergraduates or graduate students withoutprior hands-on TE experience. The experiments contained within this lab manual arebased on both classic TE experiments, such as collagen gel contraction, and modern TEtechniques, for example, using substrate rigidity to modulate cell phenotype. Theexperiments emphasize the importance of engineering analysis, mathematical modeling,and statistical design of experiments. Over 15 standalone experiments provide more thana semester’s worth of activities, allowing the instructor to customize their course.Included experiments were selected based, in part, on whether they conform to a schedulecommonly used for undergraduate lab courses. In addition, most experiments use ashared set of equipment that is commonly found in labs equipped for tissue culture. Thispaper will provide an overview of course materials within the textbook and assessmentresults collected from students who have completed the experiments.

Micou, M. K., & Kilkenny, D. M. (2012, June), Development and Assessment of a Textbook for Tissue Engineering Lab Instruction Paper presented at 2012 ASEE Annual Conference & Exposition, San Antonio, Texas. 10.18260/1-2--21198

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