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Development Of A Radiochemistry Laboratory For The Production Of Tc 99 M Using Neutron Activation

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2007 Annual Conference & Exposition


Honolulu, Hawaii

Publication Date

June 24, 2007

Start Date

June 24, 2007

End Date

June 27, 2007



Conference Session

Radiation and Radiological Engineering Education

Tagged Division

Nuclear and Radiological

Page Count


Page Numbers

12.519.1 - 12.519.13



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Paper Authors


Sheldon Landsberger University of Texas-Austin

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Dr. Sheldon Landsberger is the Coordinator of the Nuclear and Radiation Engineering Program at the University of Texas at Austin and teaches a graduate course in Nuclear and Radiochemistry.

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Jessica Rosinski University of Texas-Austin

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Paul Buckley Lewis-Clark State College

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Dan Dugan Washington State University

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James Elliston Washington State University

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Roy Filby Washigton State University

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Jeremy Lessman Washington State University

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Alena Paulenova Oregon State University

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NOTE: The first page of text has been automatically extracted and included below in lieu of an abstract



Many health care professionals increasingly rely on the use of radiopharmaceuticals in diagnosis and therapy. 99mTc is the world’s most widely used radioisotope in nuclear diagnostic imaging. A small amount of 99mTc is incorporated in a carrier molecule and injected into the patient’s blood stream which is then used for imaging. Selective accumulation of the 99mTc in specifically targeted internal organs is achieved through the design of the carrier molecule. Traditionally it is produced from fission of uranium to produce 99Mo which then decays to 99mTc. The goal of this work is to set up a comprehensive graduate radiochemistry laboratory to isolate 99mTc using the neutron activation of stable ammonium molybdenate. Included in the laboratory is an overview of the nuclear medicine information of 99mTc, the radiation dose received for specific medical diagnoses, and the construction of an efficiency curve for a germanium detector that can be used for activity measurements of other medical isotopes produced.

Landsberger, S., & Rosinski, J., & Buckley, P., & Dugan, D., & Elliston, J., & Filby, R., & Lessman, J., & Paulenova, A. (2007, June), Development Of A Radiochemistry Laboratory For The Production Of Tc 99 M Using Neutron Activation Paper presented at 2007 Annual Conference & Exposition, Honolulu, Hawaii. 10.18260/1-2--1817

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