Honolulu, Hawaii
June 24, 2007
June 24, 2007
June 27, 2007
2153-5965
Nuclear and Radiological
13
12.519.1 - 12.519.13
10.18260/1-2--1817
https://peer.asee.org/1817
457
Dr. Sheldon Landsberger is the Coordinator of the Nuclear and Radiation Engineering Program at the University of Texas at Austin and teaches a graduate course in Nuclear and Radiochemistry.
DEVELOPMENT OF A RADIOCHEMISTRY LABORATORY FOR THE PRODUCTION OF 99mTc USING NEUTRON ACTIVATION
Abstract
Many health care professionals increasingly rely on the use of radiopharmaceuticals in diagnosis and therapy. 99mTc is the world’s most widely used radioisotope in nuclear diagnostic imaging. A small amount of 99mTc is incorporated in a carrier molecule and injected into the patient’s blood stream which is then used for imaging. Selective accumulation of the 99mTc in specifically targeted internal organs is achieved through the design of the carrier molecule. Traditionally it is produced from fission of uranium to produce 99Mo which then decays to 99mTc. The goal of this work is to set up a comprehensive graduate radiochemistry laboratory to isolate 99mTc using the neutron activation of stable ammonium molybdenate. Included in the laboratory is an overview of the nuclear medicine information of 99mTc, the radiation dose received for specific medical diagnoses, and the construction of an efficiency curve for a germanium detector that can be used for activity measurements of other medical isotopes produced.
Landsberger, S., & Rosinski, J., & Buckley, P., & Dugan, D., & Elliston, J., & Filby, R., & Lessman, J., & Paulenova, A. (2007, June), Development Of A Radiochemistry Laboratory For The Production Of Tc 99 M Using Neutron Activation Paper presented at 2007 Annual Conference & Exposition, Honolulu, Hawaii. 10.18260/1-2--1817
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