June 18, 2006
June 18, 2006
June 21, 2006
11.464.1 - 11.464.13
Development of an Artificial Organ Design Course
Over the last 50 years, artificial organs have had a significant impact on the types and quality of medical care available today. In order to address this important field, the Department of Bioengineering at the Pennsylvania State University offers a course entitled “Artificial Organ Design.” This senior and graduate level course emphasizes the following objectives:
1. Understanding engineering design and problem solving techniques with special emphasis placed on the Food and Drug Administration’s design control process for medical devices.
2. Familiarity with various engineering issues surrounding the design of artificial organs including biomaterials and biocompatibility, design principles for tissue and blood contact, power systems for implanted systems, and control of artificial organs.
3. Understanding the regulatory approval process for artificial organs including codes and regulations, reliability, and device testing.
4. Application of this knowledge to the design of artificial organs including circulatory support devices, drug delivery systems, artificial lungs and oxygenators, artificial kidney, pacemakers, neural prostheses, prosthetic heart valves, orthopedic implants, bioartificial organs (tissue engineering), and cardiopulmonary bypass. These lectures demonstrate how the techniques and knowledge presented in the first part of the class are applied to the design of artificial organs. The students then complete a final design project for an artificial organ of their own choosing.
Artificial organs have a significant impact on the types and quality of medical care available today. Artificial organs treat over 4.8 million patients a year in the United States and have improved the quality of life of over 24.4 million people.1 In order to expose students to this important field, the Department of Bioengineering at the Pennsylvania State University offers a course entitled “Artificial Organs Design.”
The Department of Bioengineering at the Pennsylvania State University has its roots in the artificial heart program. This program began as a collaborative effort in 1970 between faculty members of the Colleges of Engineering and Medicine. This initial effort resulted in a pneumatic ventricular assist device that was first implanted in 1976 and was later purchased by Thoratec® Corporation (Pleasanton, CA).2 Over 2,850 implants of this device have occurred worldwide, with the longest duration of 566 days.3 Later collaborative efforts have produced a totally implantable electric left ventricular assist device4 and an electric total artificial heart.5 A
Zapanta, C., & Manning, K. (2006, June), Development Of An Artificial Organ Design Course Paper presented at 2006 Annual Conference & Exposition, Chicago, Illinois. https://peer.asee.org/62
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