Asee peer logo

Drug Delivery Experiments In The Che Curriculum

Download Paper |

Conference

2005 Annual Conference

Location

Portland, Oregon

Publication Date

June 12, 2005

Start Date

June 12, 2005

End Date

June 15, 2005

ISSN

2153-5965

Conference Session

NSF Grantees Poster Session

Page Count

11

Page Numbers

10.494.1 - 10.494.11

Permanent URL

https://peer.asee.org/14808

Download Count

27

Request a correction

Paper Authors

author page

Stephanie Farrell

Download Paper |

Abstract
NOTE: The first page of text has been automatically extracted and included below in lieu of an abstract

Session 1526

Drug Delivery Experiments in the ChE Curriculum Stephanie Farrell, Robert P. Hesketh, Mariano J. Savelski, and C. Stewart Slater Department of Chemical Engineering Rowan University

Abstract Drug Delivery is a burgeoning field that represents one of the major research and development focus areas of pharmaceutical industry today, with new drug delivery system sales exceeding 10 billion dollars per year [ 1]. Chemical Engineers play an important and expanding role in this exciting field, yet undergraduate chemical engineering students are rarely exposed to drug delivery through their coursework. To provide students with the skills directly relevant to the evolving needs of the pharmaceutical industry, this project will develop and integrate applied drug delivery coursework and experiments throughout the Rowan Engineering curriculum.

To design and produce a new drug delivery system, an engineer must fully understand the drug and material properties and the processing variables that affect the release of the drug from the system. This requires a solid grasp of the fundamentals of mass transfer, reaction kinetics, thermodynamics and transport phenomena. The engineer must also be skilled in characterization techniques and physical property testing of the delivery system, and practiced in the analysis of the drug release data.

This project aims to provide engineering students with skills relevant to the field of drug delivery. This paper describes seven modules in which students apply engineering principles to the design, preparation, characterization, and analysis of drug delivery systems. A variety of drug delivery systems are explored including tablets, transdermal delivery systems, osmotic pumps, and supercritical fluid-processed particles. Experiments were developed to investigate the rate controlling mechanisms of different types of controlled release systems and to explore drug stability and to determine shelf life.

Introduction This project comprises seven modules that introduce students to multidisciplinary engineering principles through application to drug delivery systems. This project modifies measurement techniques and laboratory experiments widely used in the pharmaceutical sciences, to teach engineering principles. Material from the seven modules is being integrated vertically into the curriculum beginning with the Freshman Clinic, then fundamental Engineering courses, followed by Junior-Senior Clinic research projects, and finally advanced level electives on pharmaceutical topics. At the freshman level, students are engaged in the scientific discovery process with exciting hands-on analysis of commercial drug delivery systems. In more advanced courses, students design and formulate drug delivery systems and investigate the variables affecting their behavior. The Junior/Senior Clinic provides an opportunity for students to perform research projects related to drug delivery in a multidisciplinary setting. A Proceedings of the 2005 American Society for Engineering Education Annual Conference and Exposition Copyright © 2005, American Society for Engineering Education

Farrell, S. (2005, June), Drug Delivery Experiments In The Che Curriculum Paper presented at 2005 Annual Conference, Portland, Oregon. https://peer.asee.org/14808

ASEE holds the copyright on this document. It may be read by the public free of charge. Authors may archive their work on personal websites or in institutional repositories with the following citation: © 2005 American Society for Engineering Education. Other scholars may excerpt or quote from these materials with the same citation. When excerpting or quoting from Conference Proceedings, authors should, in addition to noting the ASEE copyright, list all the original authors and their institutions and name the host city of the conference. - Last updated April 1, 2015