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Integration of a Computational Lab Sequence Into a Junior-level Quantitative Physiology Course

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Conference

2012 ASEE Annual Conference & Exposition

Location

San Antonio, Texas

Publication Date

June 10, 2012

Start Date

June 10, 2012

End Date

June 13, 2012

ISSN

2153-5965

Conference Session

BME Course and Curriculum Development

Tagged Division

Biomedical

Page Count

10

Page Numbers

25.816.1 - 25.816.10

Permanent URL

https://peer.asee.org/21573

Download Count

21

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Paper Authors

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Kurt A. Thoroughman Ph.D. Washington University, St. Louis

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Kurt A. Thoroughman, Ph.D., is the Associate Chair for Undergraduate Studies and an Associate Professor in the Department of Biomedical Engineering at Washington University in St. Louis. Thoroughman has joint appointments in the departments of Anatomy & Neurophysiology and Physical Therapy.

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biography

Ranjan Patrick Khan Washington University, St. Louis

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Haoxin Sun Washington University, St. Louis

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Patricia L. Widder Washington University, St. Louis

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Patricia Widder serves as Teaching Lab Coordinator in the Biomedical Engineering Department at Washington University in St. Louis. She received her B.S. degree in electrical engineering from the University of Illinois, Urbana-Champaign, and her M.S. degree in biomedical engineering from Washington University in St. Louis. Prior to her current position, she worked as an instrumentation and controls engineer for Monsanto, Co.

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Abstract

Integration of a Computational Lab Sequence Into a Junior-Level Quantitative Physiology CourseQuantitative Physiology I is a junior-level course that requires students to integrate overfoundational coursework in physics, biology, electrical and mechanical engineering, computerscience, and technical writing. Students explore current and classic models of instrumentation,nerve, muscle, and biomechanics. Preceding 2004 the course was three credits consisted of alecture- or lab-format; each week featured either traditional lectures or hands-on dry or wetlaboratories. A consequence of the either-or structure was gap generation in lecture, leading tolack of substance and theme continuity, and a lack of thought or energy preceding or followinglabs. A consequence of that structure was a lack of continuity in substance and theme of thecourse.In 2005 we expanded the course to four units and added a computational lab sequence. Theselabs were designed with several goals: - theoretical and numerical exploration of core concepts introduced in lecture - substantive preparation for ideas underlying physical labs - overall investigation and appreciation of the dynamic nature of models, above and beyond what is possible with pencil and paper - integration across the course to discover mathematical and quantitative physiological concepts that spanned individual topics and modulesStudents completed computational labs in three to four hour sessions, using Simulink as adynamic programming platform and MATLAB to drive simulations and analyze outputs.Individual labs considered elementary physical systems; simple filters and feedback systems;retinal processing; resistor-circuit models of excitable tissue; Hodgkin-Huxley formalism ofaction potential generation; and isometric and isotonic force generation of a Hill-type musclemodel. Students submitted informal lab reports that summarize model output, subsequentanalyses, and text demonstrating their understanding of the simulation and its relevance to corecourse concepts.The final computational lab session was a practicum examination. Students were given a newphysiological problem and required to build a model, analyze the results, and report insightgained from modeling. An example practicum problem was the simulation of a stretch reflex,which required explicit integration over prior sessions.This paper demonstrates two outcomes achieved by our seven years of teaching thecomputational lab sequence: the ability of students to integrate concepts from across the course,as evidenced by their computational lab reports, and the ability to generalize beyond theircomputational training, as evidenced by computational lab practicum performance.

Thoroughman, K. A., & Khan, R. P., & Sun, H., & Widder, P. L. (2012, June), Integration of a Computational Lab Sequence Into a Junior-level Quantitative Physiology Course Paper presented at 2012 ASEE Annual Conference & Exposition, San Antonio, Texas. https://peer.asee.org/21573

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