June 15, 2014
June 15, 2014
June 18, 2014
24.796.1 - 24.796.7
Interactive Web-based Virtual Environment for Learning Single-Use Biomanufacturing TechnologiesThe paper presents a highly interactive comprehensive learning environment for teaching andlearning the latest industrial scale single-used biomanufacturing production. The first simulation-based e-learning module focuses on upstream processing using completely disposable technologyand equipment. The simulations, which form the core of the module, can be run in the followingthree modes: Introduction, Practice, and Assessment.The Introduction mode enables students to explore disposable upstream processing procedures inwhich various types of bioreactors are used, as well as to get familiar with design, functions andinterconnections of major system components. Students can zoom-in on components, rotate them,and explore their parts using 3D models. The interactive workflow chart helps students to learnthe sequence of procedures and the purposes and features of each procedure.In the Practice mode students apply their acquired knowledge to assemble disposable systemsand manually conduct the processes using computer mouse and keyboard, following detailedstep-by-step instructions.In addition to simulations, the module includes links to online textbooks, presentations, technicalmanuals, Standard Operating Procedures (SOP), assessment quizzes and a variety of other onlinelearning resources that address the education and training needs of biopharmaceuticaltechnicians. All theses resources instantly available to the students provide a “just-in-time”learning experienceIn the assessment mode, performance-based and sequential self tests help students to self-controltheir knowledge and progress. Students are required to complete technological processes on theirown with minimal or no instructions and support. The program tracks the user’s actions, answersto the system-generated quizzes and records the elapsed time.Virtual activities are integrated with actual disposable systems and equipment available at thecollege biomanufacturing laboratory. Such combinations helps students better understand thepurposes of procedures they perform and enhances students’ comprehension of the underlyingchemical and biological processes.The paper will discuss integration of the e-learning environment into biomanufacturing curriculaand piloting it with Quincy College students.The virtual environment is being developed with a partial support from the Department of LaborTAACCCT Grant.Screenshot of the Virtual Single-Use Biomanufacturing Environment. The module presented inthe figure allows students to assemble a disposable bioreactor (bottom right), explore allprocedures and steps of the upstream process workflow (bottom middle) and operate the reactorusing interface controls and meters. A video clip illustrated a current step of the technologicalcycle can be played in a separate panel (middle right). Manipulating virtual 3D models of vessels,tools and materials, the student can perform actual workplace tasks online (bottom right).
Cherner, Y. E., & Van Dyke, B. R. (2014, June), Interactive Web-based Virtual Environment for Learning Single-Use Biomanufacturing Technologies Paper presented at 2014 ASEE Annual Conference & Exposition, Indianapolis, Indiana. https://peer.asee.org/20688
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