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Microfluidic Medical Diagnostics Devices: Instructive Student Projects for Product Development in the Coming Decade

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2015 ASEE Annual Conference & Exposition


Seattle, Washington

Publication Date

June 14, 2015

Start Date

June 14, 2015

End Date

June 17, 2015





Conference Session

Innovations in Upper-level Biomedical Engineering Courses

Tagged Division


Page Count


Page Numbers

26.1152.1 - 26.1152.10



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Paper Authors

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Michael G. Mauk Drexel University

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Richard Chiou Drexel University

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Portable devices and systems that enable medical diagnostics outside oftraditional laboratory settings will likely be an important component of futurehealthcare. The recent SARS and Ebola pandemics underscore the pressing needfor simple, low-cost, easy-to-use devices to rapidly test for pathogens in placessuch as airports, border crossings, schools, doctors’ offices, and clinics.Miniaturized diagnostic can be realized with microscale fluidic systems formed oncredit card-sized plastic substrates. These microfluidic “Lab on a Chip” (LOC)devices can process and analyze medical specimens (whole blood, plasma, saliva,urine), food and water, and environmental samples to detect viruses, bacteria,parasites, toxins, and bioterrorism agents. New developments in rapidprototyping (3D printers, laser cutters), Computer-Aided Design (CAD),microcontrollers, Smartphone cameras and other CCD-based imaging, miniaturesensors, freeze-drying reagents, and optical components and materials (e.g., LEDs,laser diodes, photodiodes, optical fibers, filters, fluorescent dyes) make thedesign, fabrication, and testing of Lab on a Chip diagnostics devices accessible toengineering students. We describe Student Design Projects to demonstrate LOCdiagnostics devices to meet current needs for healthcare, public safety, andsustainable development. These projects provide a gateway for engineeringstudents to learn biomedical applications of engineering, gain experience withproduct development, and integrate knowledge of materials, instrumentation,control, rapid prototyping, and applied optics in products with considerable near-term commercial potential and/or as appropriate technology for resource-limitedareas of the world.

Mauk, M. G., & Chiou, R. (2015, June), Microfluidic Medical Diagnostics Devices: Instructive Student Projects for Product Development in the Coming Decade Paper presented at 2015 ASEE Annual Conference & Exposition, Seattle, Washington. 10.18260/p.24489

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