they progress from discovery, through clinical trials, to finalrelease to the public. An overview of the steps in drug production and use was presented: activepharmaceutical ingredient (API) synthesis, drug formulation, and drug delivery. Manufacturingissues related to batch processing, multiphase drug systems, green engineering, and processingscale were included (Figure 1). This lecture was posted on the ASEE ChE Division web site(www.asse-ched.org/) as well as PharmaHUB (www.PharmaHUB.org ).7 Typical Drug Synthesis – “Campaigns” • Multi-step synthesis, transformations – Intermediate compounds • Isolations (purification) S-1 S-2 R-5 S-15
, thevelocity is zero everywhere, and for t ≥ 0, Vx at y=0 is 2 ft/s, and the fluid is water ( = 10-5ft2/s). Choose time interval of 2 sec and distance step (delta y) as 0.05 ft for the calculations. Vx Vx 2 2 t y Use discretized algebraic equivalent of the above equation and by creating a x-y grid calculatevelocity at nodes (1,1), (2,2) and (3,1). Predict laminar velocity profiles for a flow of twoadjacent fluids inside a tube.The above example problem is a typical textbook problem, however, before it was administered,author identified different concepts and concept levels (basic, moderate and advanced) anddeveloped three concept group exercises and administered them sequentially.Concept
cognitive-developmental inquiry. American Psychologist, 34(10): 906–911.6. Schraw, G., and Dennison, R. S. 1994. Assessing metacognitive awareness. Contemporary Educational Psychology, 19: 460-475.7. Stewart, P. W., Cooper. S. S., and Moulding, L. R. 2007. Metacognitive development in professional educators. The Researcher, 21(1): 32-40.8. Gassner, L. 2009. Developing metacognitive awareness: a modified model of a PBL-tutorial. Thesis for the Bachelor of Odontology in Oral Health. Malmö University. Sweden.9. Jonassen, D. H. 2010. Assembling and Analyzing the Building Blocks of Problem-Based Learning Environments, in Handbook of Improving Performance in the Workplace, Volume One: Instructional Design and
ofoperating conditions for the heater and temperature control experiments but also allows for aninteresting experimental study of the 1st and 2nd laws of thermodynamics for a flow system.Table 2 shows example data and results that demonstrate that energy is conserved and the 2nd lawis not violated in this novel device. H and S values were evaluated assuming ideal gas withtemperature dependent heat capacity. Page 23.126.8Figure 6. Example temperature readings with vortex tube in operation.Table 2. Example vortex tube data and results. Inlet Cold stream Warm stream Total Air flow mol/s 0.142
. For [this] class, um, I kind of felt like I didn’t want to do that, I didn’t want…them to just be sitting back and listening to me talk”S/he went on to describe the benefit of attending the ASEE Summer School, and specificallyher/his familiarity with and motivation to use the Concept Warehouse, “I was aware of it beforeand kind of played around with it, but uh really tried to use it a little more this semester.” Someparticipants simply described the Concept Warehouse as something that “seemed like a greatidea.” In other cases, participants cited previous experience with pedagogy as a contributingfactor to their implantation of the Concept Warehouse, such as the following statement from oneparticipant, “I was already familiar with the
educational outcomeswithout students having to spend sleepless nights in the campus computer room, or isolated inthe corner with their calculator, spewing numbers out. The contents of this paper weredeveloped over many years of teaching a variety of chemical engineering courses where use of Page 23.468.2process simulation facilitates the incorporation of real world design experiences into theclassroom.Background of Process Simulation at Mississippi State UniversityAt Mississippi State University (MSU), a discussion of the curriculum in the early 90’s focusedon numerical analysis tools and how best to educate students in their use. At that time
oxidation and pyrolysis) makes contact with biomass from the feeding chute. During the process, free moisture and cell- bound water in the biomass are removed by evaporation. The up-flowing gas mixture consists of 29% H2, 34% CO, 17% CO2, 15% CH4 and 5% H2O, all in mol %. If the heat transfer in this process is 108 kJ/s, the up-flowing gas mixture enters the heating zone at a steady rate of 350… Figure 2 Schematic diagram of an updraft gasifier Page 23.69.8 mol/s at 800oC, what is the temperature of the gas mixture leaving the heating zone? Solution: (omitted)【Homework Problems】 Totally 10
developed in the 1930’s and 1940’s3, 4, basic concepts of thermally coupledcolumns are not typically taught in undergraduate separations courses. Although they are taughtin some design courses, they are not included in the design courses at Mississippi StateUniversity. Due to the renewed interest in process intensification, a module on thermallycoupled columns is being added to an undergraduate separations course. Page 23.177.3ImplementationThe class is a junior level separations course that focuses on equilibrium staged operations,particularly distillation columns. This one semester course includes flash distillation, short-cutand rigorous
. The liquid stream from the heater is recycled and is mixed with the fresh water to form the water feed entering the scrubber. Find the unknown values for all streams? Page 23.1298.6The solution contained a number of intentional errors. Attached to the solution was asmall packet of Post-it®’s in one of four different colors. The students were given tenminutes to examine the solution, find areas where they disagreed with the solution, writeon a Post-it® where they disagreed with solution, what the disagreement was, and how tochange the solution to resolve the disagreement. Each place where they found adisagreement was to be noted on a separate
technology schemes. o Second, describe the theory and physics considered when simulating each functional unit of your device. This should be included just after the description of each unit. § State the physics (i.e. creeping flow) and give the equation. Define terms and explain why relevant to the functionality of your device. § Describe the boundary conditions – equations are preferable. Justify and explain the assumptions. § Describe the parameters varied. For example, flow rates from 1 to 10 um/s were simulated. o Include a table/other to succinctly and clearly organize your simulation conditions &
first and second-year chemical engineering students. Dr. Ramirez’s main subjects include Material Balances, Energy Balances, and Thermodynamics. She also teaches to students from the master’s program in Education using Technology at the Universidad Virtual del Tecnol´ogico de Monterrey. She has worked on projects with Canam-Romisa, Danisco Ingredients S.A. de C.V., GBM-Grupo Bioqu´ımico Mexicano,. Grupo Industrial Chihuahua S. A. and Siemens. She was trained in Problem Based Learning strategy by the Wheeling Jesuit University-NASA at Wheeling, West Virginia. Dr. Ramirez has several publications, including the chapter ”El profesor como agente de cambio a trav´es del trabajo colaborativo” (Translated: The teacher as an
bookexam. (Author’s note: we are working on further statistical analysis to discern the effect). Page 23.999.11References[1]Smith, J. M.; Van Ness, H. C.; Abbott, M.M.; Introductions to Chemical Engineering Thermodynamics, McGrawHill, 7th Edition, February 1 2005.[2]Bruneau J.; Techniques to increase student reading, Wakonse, May 24-29, Muskegon, 2012.[3]Fry, S. W., and Villagomez, A. Writing to Learn: Benefits and Limitations. College Teaching, Vol 60, No 4, p170-175 (2012).[4]Mosteller, F., The “Muddiest Point in the Lecture” as a Feedback Device. On Teaching and Learning, Volume 3,ege Teaching, Vol 3, p 10-21 (1989).[5] Pryor, J.H., Eagan, K
engineering.References1. am Ende, D. (ed) Chemical Engineering in the Pharmaceutical Industry: R&D to Manufacturing. Wiley, 2010.2. http://pharmeng.rutgers.edu/ [accessed 1/7/2013]3. http://chemicaleng.njit.edu/academics/graduate/masters/pharm.php [accessed 1/7/2013]4. Farrell, S., Slater, CS., Gephardt, ZO., Savelski, MJ. Workshop Modules on Pharmaceutical Engineering forUndergraduate Education. Proceedings of the 2012 ASEE Conference & Exposition, San Antonio, TX, 2012.5. Cavanagh, DP, Wagner JJ. A Three-Week Hands-On Introduction to Biotransport & Drug Delivery for First-YearEngineering Students. Proceedings of the 2005 ASEE Conference & Exposition, Salt Lake City, UT, 2004.6. Allen, LV. Popovich, N., Ansel, HC. Ansel’s Pharmaceutical Dosage
. Carletta, J., Bayles T.M., Kalveram, K., Khorbotly, S., Macnab, C., Nazhandali, L., Rice, J., Smith, J.A., Turner, L.E., Williams, S. and L. Wyard-Scott, “Special Session – Real World Engineering Projects: Discovery-Based Curriculum Modules for First-Year Students”, Paper published in the Proceedings of the 39th ASEE/IEEE Frontiers in Education Conference; presented in session T1A, San Antonio, TX, October, 2009. 3. Bayles, T.M., “Introduction to Engineering Design: An Emphasis on Communication”, Paper AC-2009-1482 published in the 2009 ASEE proceedings and presentation in the Freshman Programs Division, San Antonio, TX, June 2009. 4. https://academicskills.anu.edu.au/resources/handouts/writing-reflective-marker
organization, data interpretation, and analysis. Using an online simulationprovides an outlet for collection of data within constraints of a stand-alone technical writingcourse: limited time and laboratory equipment resources; and is an effective way to engagestudents in laboratory report writing.Works Cited1 Atman, Cynthia J., Sheri D. Sheppard, Jennifer Turns, Robin S. Adams, Lorraine N. Fleming, ReedStevens, Ruth A. Streveler, Karl A. Smith, Ronald L. Miller, Larry J. Leifer, Ken Yasuhara, & Dennis Lund. (2010).Enabling engineering student success: The final report for the center for the advancement of engineering education.San Rafael, CA: Morgan & ClaypoolPublishers. (http://www.engr.washington.edu/caee/CAEE%20final%20report
industrial and student side.However, now that the course itself it better established, more instructor time should beavailable to coordinate such activities. A related stretch goal is to have the problemsthemselves proposed by local industry. This has not been attempted in part due to thelimited ‘laboratory’ available for the class, but will hopefully be an option for futureofferings as plans for addition of a kitchenette to one of the classrooms are underway. Page 23.929.9Bibliography 8 1. Armstrong RC, Brennecke J, Butts S et al. How is the Discipline of
. 3 -8 2Surface concentration of PCE is 2 g/m of soil. Diffusivity of PCE in soil is 8.8 x 10 m /s. Student teams were asked to develop an emergency management plan for a lab (teachingor research lab) in the department. They were asked to do a walk-around of the space anddetermine the locations of nearest eye wash, safety shower, first aid kits, and spill kits. Theywere also asked to identify emergency exit routes, rally points, and emergency contactinformation for that space. Students used the lab space floor plan to mark the location of safetydevices and kits, and to chart emergency routes. Example of an emergency management plan isgiven in figure 5. Student teams then compared their
to be evacuated.For the thorough safety review, students are asked to include the following additionalinformation: 1. a flow diagram showing key valves, pumps, feed and product tanks; 2. material compatibility information and general operating limits for the stand and auxiliary equipment (as shown in Table 3); 3. a simple What If analysis including at least three possible failure modes (as shown in Table 4) and any recommendations and action items that require attention from the safety perspective. Table 1. List of starting materials, additives, products, and by-products for the experiment. ID Chemical Name(s) Function in the Process 1 2
times during its life. Plantoperations are, in principle, addressed in the traditional process control course(s) in theundergraduate curriculum. However, the operability of complete processes is usually outside thescope of these courses.An observation from teaching process design over a period of approximately 25 years is thatstudents have become increasing adept at using computer software and performing increasinglycomplex simulations using simulator software. Parametric optimization and extensive heatintegration are examples of improvements that can be and that are now easily simulated butwould have been nearly impossible or prohibitively time consuming only 25 years ago. Thisimprovement in software acuity seems to come at the price of
course in 19651. Thestructure for this report draws heavily on previous reports published on behalf of the EducationDivision.2,3,4The survey was conducted via internet server hosted by the University of Kentucky runningLimeSurvey (limesurvey.org). E-mail invitations to participate were initially sent to all 158department chairs in the United States and later those in Canada requesting participation from thefaculty members teaching the relevant course(s). A number of instructors outside of NorthAmerica were also invited to participate. A separate request was sent to the instructors of recordfor senior design course during the 2011-2012 academic year based on information posted online
international students. I will continue to utilize elements of theproblem-based learning methodology, but I will not be adding it to all courses.References 1. Mayer, R.E. & Greeno, J.G. (1972). Structural differences between learning outcomes produced by different instructional methods. Journal of Educational Psychology, 63, 165-173. 2. Hmelo-Silver, C.E., Duncan, R.G. & Chinn, C.A. (2007). Scaffolding and achievement in problem-based and inquiry learning: A response to Kirschner, Sweller, and Clark (2006). Educational Psychologist, 42(2), 99-107. Page 23.309.9 3. Albanese, M.A. & Mitchell, S
. i Felder, R.M., “Stoichiometry without Tears”, Chemical Engineering Education, 24(4), 188‐196, 1990. ii Maharaj, S. and L. Banta, “Using Log Assignments to Foster Learning: Revisiting Writing across the Curriculum”, Journal of Engineering Education, January 2000, 73‐78. iii Sharp, J., J. Harb, and R. Terry, “Combining Kolb Learning Styles and Writing to Learn in Engineering Classes”, Journal of Engineering Education, April 1997, 93‐101. iv Felder, R. and R. Brent, “Writing Assignments – Pathways to Connections, Clarity, Creativity, College Teaching,” College Teaching 40(1), 1992, 43‐47. v Burrows, V., B. McNeill, N. Hubele, and L. Bellamy, “Statistical Evidence for Enhanced Learning of
. (1996) Alternative FuelTransit Bus Evaluation Program Results. International Spring Fuels and Lubricant Meeting. Dearborn, MI. SAEPaper No. 961082. Retrieved December 28, 2012, fromhttp://web.missouri.edu/~schumacherl/Collection_and_Collation_of_Performance_Data.pdf.16 Schumacher, L G. (1995). Biodiesel Emissions Data From Series 60 DDC Engines. American Public TransitAssociation Bus Operations and Technology Conference. Reno, NV. Retrieved December 28, 2012, fromhttp://web.missouri.edu/~schumacherl/Collection_and_Collation_of_Performance_Data.pdf.17 Marshall, W., Schumacher, L.G, Howell, S. A (1995) Engine Exhaust Emissions Evaluation of a Cummins L10EWhen Fueled with a Biodiesel Blend. SAE Paper No. 952363. SAE, Warrendale, PA. Retrieved
of soybean oil, J. Am. Oil Chem. Soc., 74, 1457-1463(1997).5. Gunvachai, K., Hassan, M. G., Shama, G., and Hellgardt, K., A new solubility model to describe biodieselformation kinetics, Trans. IChemE, Part B, 85(B5), 383-389, (2007).6. Slinn, M. and Kendall, K., Developing the reaction kinetics for a biodiesel reactor, Bioresource Technology, 100,2324-2327, (2009).7. Vicente, G., Martinez, M., Aracil, J., and Esteban, A., Kinetics of sunflower oil methanolysis, Ind. Eng. Chem.Res., 44, 5447-5454, (2005).8. Stamenkovic, O. S., Todorovic, Z. B., Lazic, M. L., Veljkovic, V. B., and Skala, D. U., Kinetics of sunflower oilmethanolysis at low temperatures, Bioresource Technology, 99 (2008) 1131-1140, (2008).9. He, B. B., Singh, A. P., and Thompson
, and Research Bases." Journal of Engineering Education 25.123(2006)Prince, Michael J., Vigeant, M., and Nottis, K., “A Preliminary Study on the Effectiveness ofInquiry-Based Activities for Addressing Misconceptions of Undergraduate Engineering Students”,Education for Chemical Engineers, 4:29 (2009)Schuck, S., Kearney, M., and Aubusson, P., “Education Opportunities and Challenges forGeneration OurSpace: Taming the beast?”, Proceedings of World Conference on EducationalMultimedia, Hypermedia, and Telecommunications, 5804, 2008Vigeant, M., Prince, M., and Nottis, K., “Creating of Reliable Instruments for Assessment ofConceptual Understanding in Heat Transfer and Thermodynamics”, AIChE Annual Meeting, 2009Vigeant, M., Prince, M., and Nottis, K
andReactions, Industrial Heating, BNP Media, Pittsburgh, PA: August 1982.10. Fogler, H. S. Elements of Chemical Reaction Engineering. 4th Edition. Prentice Hall, Upper SaddleRiver, NJ, 2009. Page 23.1314.11
Brent. ASQ Higher Education Brief. Volume 2, No. 4, August 2009.15. http://jimi.cbee.oregonstate.edu/concept_warehouse/16. Applications, Reliability and Validity of the Index of Learning Styles. Richard M. Felder and Joni Spurlin. International Journal of Engineering Education. Volume 21, No. 1, pp. 103-112, 2005.17. A Psychometric Study of the Index of Learning Styles. Thomas A. Litzinger, Sang Ha Lee, John C. Wise and Richard M. Felder. Journal of Engineering Education. Volume 96, No. 4, pp. 309-319, 2007.18. A Contribution to Validation of Score Meaning for Felder-Soloman’s Index of Learning Styles. Malgorzata S. Zywno. Proceedings of the 2003 American Society for Engineering Education Annual Conference &