Aviles Vargas, A. S., & Sun, G. (2024, March), Development and Optimization of a 3D-Printed Microfluidic Device with Enhanced Transparency for Bioimaging Applications  Paper presented at 2024 ASEE-GSW, Canyon, Texas. 10.18260/1-2--45371

\bibitem{asee_peer_45371}
  Aviles Vargas, A. S., \& Sun, G. (2024, March), \emph{Development and Optimization of a 3D-Printed Microfluidic Device with Enhanced Transparency for Bioimaging Applications}
  Paper presented at 2024 ASEE-GSW, Canyon, Texas.
  10.18260/1-2--45371

Ana Sofia Aviles Vargas and Gongchen Sun.  "Development and Optimization of a 3D-Printed Microfluidic Device with Enhanced Transparency for Bioimaging Applications".  2024 ASEE-GSW, Canyon, Texas, 2024, March.  ASEE Conferences, 2024.  https://peer.asee.org/45371 Internet.  21 Dec, 2024

\bibitem{asee_peer_45371}
  Ana Sofia Aviles Vargas and Gongchen Sun.
  "Development and Optimization of a 3D-Printed Microfluidic Device with Enhanced Transparency for Bioimaging Applications".
  \emph{2024 ASEE-GSW, Canyon, Texas, 2024, March}.
  ASEE Conferences, 2024.
  https://peer.asee.org/45371 Internet.  21 Dec, 2024

@INPROCEEDINGS{asee_peer_45371
author = "Ana Sofia Aviles Vargas and Gongchen Sun"
title = "Development and Optimization of a 3D-Printed Microfluidic Device with Enhanced Transparency for Bioimaging Applications"
booktitle = "2024 ASEE-GSW"
year = "2024"
month = "March"
address = "Canyon, Texas"
publisher = "ASEE Conferences"
note = {https://peer.asee.org/45371}
number = {10.18260/1-2--45371}
}

TY  - CPAPER
AB  - This project, grounded in Biomaterials and Bioinstrumentation courses within Biomedical Engineering, aims to enhance the optical transparency and resolution of microfluidic devices fabricated using low-cost digital light processing (DLP) 3D printing. Prioritizing affordability and accessibility, we modified a commercially available 3D printer (Phrozen Sonic Mini 8K) by substituting the build plate with surface-treated glass slides. These slides underwent surface treatment to effectively modify their hydroxy-group-rich surface with a hydrophobic agent (3-(Trimethoxysilyl)propyl methacrylate (TSMPMA)) under oxygen plasma. Additionally, the z-axis limit switch was adjusted to accommodate the thickness of the glass slide on the build plate. Our method significantly improves transparency and resolution, enabling precise segmentation of micro-scale objects from analyzed images obtained through a microscope. The enhanced optical clarity and microchannel resolution of the device can facilitate imaging and characterization of microparticles, thus paving the way for high-throughput cell sorting applications. This interdisciplinary approach integrates knowledge from core Biomedical Engineering courses, emphasizing applications in cell and bioimaging.

AU  - Ana Sofia Aviles Vargas
AU  - Gongchen Sun
CY  - Canyon, Texas
DA  - 2024/03/10
PB  - ASEE Conferences
TI  - Development and Optimization of a 3D-Printed Microfluidic Device with Enhanced Transparency for Bioimaging Applications
UR  - https://peer.asee.org/45371
DO  - 10.18260/1-2--45371
ER  -